AI-Augmented · CRO · CDMO · Advanced Modalities

Integrated Chemistry.
From Discovery
to Manufacture.

Astinova Bio Labs pairs AI-augmented route design with expert wet-lab synthesis across complex modalities — small molecules, PROTACs, ADCs, macrocycles, and beyond. Our engine proposes; a PhD chemist verifies, scales and costs every route. One partner. Every stage.

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500+ Compounds Synthesized
4 Advanced Modality Platforms
End-to-End CRO-CDMO Capabilities
Expert Synthesis Teams
Our Services

End-to-End Chemistry Services

From early-stage hit identification to multi-gram manufacturing, we support every phase of your drug development program.

Discovery (CRO)

Medicinal chemistry, hit-to-lead optimization, SAR campaigns, and custom synthesis for your discovery programs.

  • Medicinal Chemistry
  • Hit-to-Lead & SAR
  • Scaffold Design
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Development (CMC)

Route scouting, process optimization, impurity profiling, and regulatory documentation for CMC packages.

  • Process Optimization
  • Analytical Development
  • Scale-up Support
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Manufacturing (CDMO)

Custom synthesis, GMP-ready manufacturing, multi-step complex synthesis with full batch documentation.

  • Custom Synthesis
  • GMP-Ready Manufacturing
  • Quality Control
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Synthesis Intelligence

AI-Augmented Route Design

Raw AI retrosynthesis is not a decision. Our engine proposes, a curated knowledge base grounds it, and a PhD chemist verifies every route — so you get a deliverable you can fund, run and stand behind. Automation makes us fast; expertise makes us right.

01

AI Engine

Curated retrosynthesis search — Neural MCTS on the USPTO corpus — proposes candidate routes in seconds.

02

Grounded Knowledge

Curated industrial templates, an FDA drug-synthesis corpus (2002–2022) and citable textbook retrieval anchor the chemistry.

03

Expert Curation

A PhD synthetic chemist corrects, scale-matches and costs every route before it ships.

04

Verified Report

A cited, hazard-aware, scale-matched deliverable — citations and CAS verified, never guessed.

Specialty Platforms

Advanced Modality Chemistry

Deep expertise in the complex chemistry that modern drug discovery demands.

PROTACs & Molecular Glues

  • Ligand-linker-payload design
  • 10–20+ step synthesis
  • E3 ligase ligands (VHL, CRBN)
  • Linker library design
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ADCs / DACs

  • Linker & payload synthesis
  • Conjugation-ready components
  • Cleavable & non-cleavable linkers
  • Cytotoxic payload analogs
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Small Molecules

  • NCE route design & scaffold analysis
  • Multi-scale routes: lab · kilo · commercial
  • Generic API routes (patent-grounded)
  • Cost, hazard & IP-aware selection
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Macrocycles & Asymmetric Synthesis

  • Multi-chiral center control
  • >99% ee achievable
  • Macrolactamization
  • Atroposelective synthesis
Learn more →
Why Choose Us

The Astinova Difference

Built on deep chemistry expertise and a commitment to partnership.

Complex Chemistry Expertise

Deep know-how in multi-step, multi-chiral, and challenging synthetic routes for advanced modalities.

Integrated Platform

Seamless discovery-to-manufacture workflow eliminates costly handoffs and knowledge gaps.

Speed & Scale

Rapid turnaround from milligram to multi-gram scale, designed around your program timelines.

Quality & Compliance

Rigorous analytical characterization, impurity profiling, and documentation aligned with regulatory standards.

Ready to Accelerate Your Program?

Tell us about your chemistry challenge. Our team will respond within 48 hours.

Partner With Astinova