Chemical Catalog

Chemical Catalog &
Custom Building Blocks

A growing portfolio of small-molecule and advanced-modality building blocks, intermediates and custom synthesis standards — the chemistry behind our AI-driven, PhD-verified route design — available on request.

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PROTAC Building Blocks

E3 Ligase Ligands

  • ›VHL ligand (VH032 analog)
  • ›Pomalidomide (CRBN)
  • ›Lenalidomide derivatives
  • ›Bestatin analogs (IAP)

Available on request

PEG Linkers

  • ›PEG1–PEG12 diamine
  • ›Boc-PEG-acid series
  • ›NH2-PEG-NHS ester
  • ›Azide-PEG-amine

Available on request

Alkyl & Mixed Linkers

  • ›C2–C8 diamine linkers
  • ›Piperazine linkers
  • ›Piperidinyl linkers
  • ›Mixed alkyl-PEG hybrids

Available on request

Reactive Handles

  • ›NHS-ester activated acids
  • ›Alkyne-bearing warheads
  • ›Azide-functionalized components
  • ›Amine-reactive probes

Available on request

ADC Components

Cleavable Linkers

  • ›Val-Cit-PABC linkers
  • ›Disulfide-based linkers
  • ›Acid-labile hydrazide linkers
  • ›β-glucuronide linkers

Available on request

Non-Cleavable Linkers

  • ›Maleimide-caproyl linkers
  • ›NHS-PEG4-maleimide
  • ›Thioether stable linkers
  • ›Bifunctional crosslinkers

Available on request

Payload Analogs

  • ›Auristatin analogs (MMAE-type)
  • ›Maytansinoid analogs (DM1-type)
  • ›Novel cytotoxin intermediates
  • ›Stated scale caps per compound

Custom synthesis

Conjugation Handles

  • ›Thiol-reactive maleimides
  • ›Amine-reactive NHS esters
  • ›Aldehyde-reactive hydrazides
  • ›Click-chemistry handles

Available on request

Small-Molecule Building Blocks

Scaffolds & Fragments

  • ›Saturated heterocyclic cores
  • ›Spirocyclic building blocks
  • ›sp3-rich fragment sets
  • ›Functionalized azetidines & pyrrolidines

Available on request

Advanced Intermediates & KSMs

  • ›Custom key starting materials
  • ›Late-stage NCE intermediates
  • ›Generic-API intermediates (patent-grounded)
  • ›Multi-step custom synthesis

Custom synthesis

Reference Standards

  • ›Impurity standards
  • ›Isotope-labeled compounds
  • ›Metabolite standards
  • ›Characterized to specification

Available on request

Coupling Partners

  • ›Boronic acids & esters
  • ›Halide coupling partners
  • ›Protected amino acids
  • ›Chiral auxiliaries

Available on request

Full catalog available on request. Contact us to discuss specific compound needs.

Request the Catalog