Accelerate your discovery programs with AI-augmented route design and Astinova's expert medicinal chemistry team — from hit identification and small-molecule NCE route design through optimized leads ready for development. The engine proposes; a PhD chemist verifies, scales and costs every route.
Comprehensive medicinal chemistry and custom synthesis capabilities — grounded by a curated retrosynthesis engine (Neural MCTS on the USPTO corpus, an FDA drug-synthesis corpus and citable textbook retrieval) and verified by PhD chemists — to support your discovery-stage programs.
Expert medicinal chemistry support for your hit-to-lead and lead optimization programs, including analog design, synthesis, and SAR interpretation.
Rapid synthesis of focused libraries and analogs to define SARs, optimize potency, and identify lead candidates.
Systematic SAR exploration campaigns with rapid analog synthesis and comprehensive analytical characterization.
Bespoke synthesis of challenging molecules, novel scaffolds, reference standards, and specialized intermediates.
Design and synthesis of novel scaffolds with built-in vectors for efficient SAR exploration and property optimization.
Synthesis and elaboration of fragment hits, fragment-to-lead chemistry, and linker-based fragment merging strategies.
Our discovery chemistry team is equipped to handle diverse synthetic challenges.
A collaborative, science-driven engagement model designed around your program needs.
Share your target, chemistry challenge, timeline, and desired quantities. We sign an NDA on day one.
We propose a synthesis strategy, timeline, milestones, and deliverables within 48 hours.
Weekly updates, real-time data sharing, and collaborative design iterations throughout the campaign.
Compounds delivered with full characterization data and a detailed synthesis report.
Share your chemistry challenge and we'll get back to you within 48 hours with a proposal.
Request a Proposal